Selected Publications


Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy. 

Kau AL, Planer JD, Liu J, Rao S, Yatsunenko T, Trehan I, Manary MJ, Liu TC, Stappenbeck TS, Maleta KM, Ashorn P, Dewey KG, Houpt ER, Hsieh CS, Gordon JI.

Science translational medicine. 2015; 7(276):276ra24. Pubmed/PDF


Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice. 

Planer JD, Peng Y, Kau AL, Blanton LV, Ndao IM, Tarr PI, Warner BB, Gordon JI.

Nature. 2016; 534(7606):263-6. Pubmed/PDF


Human nutrition, the gut microbiome and the immune system. 

Kau AL*, Ahern PP*, Griffin NW, Goodman AL, Gordon JI.

Nature. 2011; 474(7351):327-36. Pubmed/PDF


Additional Publications

Gut microbiomes of Malawian twin pairs discordant for kwashiorkor. Smith MI, Yatsunenko T, Manary MJ, Trehan I, Mkakosya R, Cheng J, Kau AL, Rich SS, Concannon P, Mychaleckyj JC, Liu J, Houpt E, Li JV, Holmes E, Nicholson J, Knights D, Ursell LK, Knight R, Gordon JI. Science (New York, N.Y.). 2013; 339(6119):548-54. PubMed/PDF

Gut microbiota from twins discordant for obesity modulate metabolism in mice. Ridaura VK, Faith JJ, Rey FE, Cheng J, Duncan AE, Kau AL, Griffin NW, Lombard V, Henrissat B, Bain JR, Muehlbauer MJ, Ilkayeva O, Semenkovich CF, Funai K, Hayashi DK, Lyle BJ, Martini MC, Ursell LK, Clemente JC, Van Treuren W, Walters WA, Knight R, Newgard CB, Heath AC, Gordon JI. Science (New York, N.Y.). 2013; 341(6150):1241214. PubMed/PDF

NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis. Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon JI, Flavell RA. Cell. 2011; 145(5):745-57. PubMed/PDF

Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity. Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ, Camporez JP, Shulman GI, Gordon JI, Hoffman HM, Flavell RA. Nature. 2012; 482(7384):179-85. PubMed/PDF

Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus. Perry JS, Lio CW, Kau AL, Nutsch K, Yang Z, Gordon JI, Murphy KM, Hsieh CS. Immunity. 2014; 41(3):414-26. Pubmed/PDF

Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications. Yilmaz P, Kottmann R, Field D, Knight R, Cole JR, Amaral-Zettler L, Gilbert JA, Karsch-Mizrachi I, Johnston A, Cochrane G, Vaughan R, Hunter C, Park J, Morrison N, Rocca-Serra P, Sterk P, Arumugam M, Bailey M, Baumgartner L, Birren BW, Blaser MJ, Bonazzi V, Booth T, Bork P, Bushman FD, Buttigieg PL, Chain PS, Charlson E, Costello EK, Huot-Creasy H, Dawyndt P, DeSantis T, Fierer N, Fuhrman JA, Gallery RE, Gevers D, Gibbs RA, San Gil I, Gonzalez A, Gordon JI, Guralnick R, Hankeln W, Highlander S, Hugenholtz P, Jansson J, Kau AL, Kelley ST, Kennedy J, Knights D, Koren O, Kuczynski J, Kyrpides N, Larsen R, Lauber CL, Legg T, Ley RE, Lozupone CA, Ludwig W, Lyons D, Maguire E, Methé BA, Meyer F, Muegge B, Nakielny S, Nelson KE, Nemergut D, Neufeld JD, Newbold LK, Oliver AE, Pace NR, Palanisamy G, Peplies J, Petrosino J, Proctor L, Pruesse E, Quast C, Raes J, Ratnasingham S, Ravel J, Relman DA, Assunta-Sansone S, Schloss PD, Schriml L, Sinha R, Smith MI, Sodergren E, Spo A, Stombaugh J, Tiedje JM, Ward DV, Weinstock GM, Wendel D, White O, Whiteley A, Wilke A, Wortman JR, Yatsunenko T, Glöckner FO. Nature biotechnology. 2011; 29(5):415-20. PubMed/PDF

Immune dysregulation underlies a subset of patients with chronic idiopathic pruritus. Xu AZ, Tripathi SV, Kau AL, Schaffer A, Kim BS. Journal of the American Academy of Dermatology. 2016; 74(5):1017-20. PubMed

Anti-interleukin 4 and 13 for asthma treatment in the era of endotypes. Kau AL, Korenblat PE. Current opinion in allergy and clinical immunology. 2014;14(6):570-5. Pubmed/PDF

Pilin and sortase residues critical for endocarditis- and biofilm-associated pilus biogenesis in Enterococcus faecalis. Nielsen HV, Flores-Mireles AL, Kau AL, Kline KA, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ. Journal of bacteriology. 2013; 195(19):4484-95. Pubmed/PDF

Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development. Guiton PS, Hung CS, Kline KA, Roth R, Kau AL, Hayes E, Heuser J, Dodson KW, Caparon MG, Hultgren SJ. Infection and immunity. 2009; 77(9):3626-38. PubMed/PDF

Kline KA*, Kau AL*, Chen SL, Lim A, Pinkner JS, Rosch J, Nallapareddy SR, Murray BE, Henriques-Normark B, Beatty W, Caparon MG, Hultgren SJ. Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis. Journal of bacteriology. 2009; 191(10):3237-47. PubMed/PDF

Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice. Kau AL, Martin SM, Lyon W, Hayes E, Caparon MG, Hultgren SJ. Infection and immunity. 2005; 73(4):2461-8. PubMed/PDF

Interaction of uropathogenic Escherichia coli with host uroepithelium. Kau AL, Hunstad DA, Hultgren SJ. Current opinion in microbiology. 2005; 8(1):54-9. PubMed

Complete Pubmed bibliography